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miRNA
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SO_0000276 |
[Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene (or the product of other non coding RNA genes. Micro RNAs are produced from precursor molecules (SO:0001244) that can form local hairpin structures, which ordinarily are processed (usually via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.] |
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stratification biomarker
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BMONT_0000053 |
[A stratification biomarker is a biological characteristic or measurement used to categorize individuals into different subgroups based on their likelihood of responding to a particular treatment or exhibiting certain disease characteristics. These biomarkers are especially valuable in the context of personalized or precision medicine, where treatments can be tailored to individual patients based on their unique characteristics.] |
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prediction model
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BMONT_0000054 |
[A prediction model, also known as a predictive model or forecasting model, is a statistical or computational tool used to make predictions or forecasts about future events or outcomes based on historical data and patterns. Prediction models are widely used across various fields, including finance, healthcare, marketing, weather forecasting, and sports analytics, among others. These models leverage patterns and relationships within the data to make predictions about future behavior or events.] |
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amyloid deposition measurement
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EFO_0008351 |
[quantification of some aspect of the deposition of amyloid proteins in an organ] |
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estradiol
|
CHEBI_23965 |
[A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17.] |
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Leukoaraiosis
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OMIT_0024149 |
[Non-specific white matter changes in the BRAIN, often seen after age 65. Changes include loss of AXONS; MYELIN pallor, GLIOSIS, loss of ependymal cells, and enlarged perivascular spaces. Leukoaraiosis is a risk factor for DEMENTIA and CEREBROVASCULAR DISORDERS.] |
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metastatic malignant neoplasm in the lymph nodes
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MONDO_0005438 |
[The spread of a malignant neoplasm to the lymph nodes.] |
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false negative rate
|
STATO_0000220 |
[the false negative rate is a data item which denotes the proportion of missed detection of elements known to be meeting the detection criteria] |
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atherosclerosis
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MONDO_0005311 |
[Build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen.] |
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Unsteady gait
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HP_0002317 |
|
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neoplastic, non-malignant
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PATO_0002096 |
[A disposition inhering in a tumour by virtue of the bearer's disposition not to progress, invade surrounding tissues or metastasize.] |
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cross-validation testing
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BMONT_0000041 |
[Cross-validation or out-of-sample testing is a technique that is used to ensure that a model is robust if separate training and test data sets are not available.] |
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composite biomarkers
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BMONT_0000042 |
[Composite biomarkers, also known as multimarker panels or signatures, are combinations of multiple individual biomarkers that are used collectively to assess biological processes, disease states, or responses to treatments. These biomarkers can be diverse, including genetic, molecular, cellular, or clinical markers.] |
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regulatory standard
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BMONT_0000043 |
[A regulatory standard refers to a set of rules, guidelines, specifications, or requirements established by regulatory authorities to ensure the safety, efficacy, quality, and compliance of products, services, processes, or systems within a particular industry or jurisdiction. Regulatory standards play a critical role in protecting public health, safety, and welfare, promoting fair trade practices, and maintaining consumer confidence in regulated sectors.] |
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Document
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NCIT_C19498 |
[A physical object, or electronic counterpart, that is characterized by containing writing which is meant to be human-readable.] |
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regulatory guideline
|
BMONT_0000044 |
[Regulatory guidelines are documents issued by regulatory authorities or standardization organizations to provide recommendations, interpretations, instructions, or best practices for complying with regulatory requirements, industry standards, or established norms within a specific jurisdiction or field of activity. These guidelines offer guidance to regulated entities, stakeholders, and practitioners on how to interpret, implement, and adhere to applicable regulations, standards, or policies effectively.] |
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biomarker qualification
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BMONT_0000046 |
[Qualification is the evidentiary process of linking a biomarker with biological processes and clinical end points.] |
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cardiac function
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BMONT_0000047 |
[Cardiac function refers to the hearts capability to fulfill its task as the motor or pump of the blood circuit satisfying the bodies demands of oxygen and nutritive substances as well as the removal of waste products.] |
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clusterin
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PR_000005615 |
[A protein that is a translation product of the human CLU gene or a 1:1 ortholog thereof.] |
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systolic function
|
BMONT_0000049 |
[Systolic function refers to the heart's ability to throw out a specific amount of blood in a certain amount of time.] |