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anatomical entity
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UBERON_0001062 |
[Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.] |
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companion diagnostics
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BMONT_0000025 |
[When a biomarker test is designed to be used in conjunction with specific treatment, the test is known as a CDx. Safety and efficacy of the new drug and of the CDx are typically demonstrated in the same clinical trial for both the drug and the test.] |
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complementary diagnostics
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BMONT_0000026 |
[Complementary diagnostics are tests that, although not needed for the prescription of the corresponding therapeutic product, provide useful information on the drug risk/benefit in specific patient subsets] |
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obesity
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DOID_9970 |
[An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.] |
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Japan’s Pharmaceuticals and Medical Devices Agency
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BMONT_0000028 |
[Pharmaceuticals and Medical Devices Agency (PMDA) is Japanese regulatory agency, working together with Ministry of Health, Labour and Welfare. Its obligation is to protect the public health by assuring safety, efficacy and quality of pharmaceuticals and medical devices. Conduct scientific reviews of marketing authorization application of pharmaceuticals and medical devices, monitoring of their post-marketing safety. PMDA is also responsible for providing relief compensation for sufferers from adverse drug reaction and infections by pharmaceuticals or biological products.] |
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chronic pain biomarker
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BMONT_0000029 |
[Biomarkers that represent acute and chronic pain, predisposition to develop chronic pain and , and pain chronification, recovery and treatment outcomes.] |
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chromatid break measurement
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EFO_0007593 |
[Quantification of the level of DNA strand breaks in a cell, for example induced by an antineoplastic agent such a bleomycin. Chromatid breaks can be assessed under the microscope in dividing cells during metaphase.] |
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Healthy Control
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NCIT_C94342 |
[A healthy subject that is matched with an affected individual in a trial.] |
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digestive system disorder
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MONDO_0004335 |
[A disease or disorder that involves the digestive system.] |
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disorder
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OGMS_0000045 |
[A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease.] |
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one-dimensional temporal region
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BFO_0000038 |
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acute coronary syndrome
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MONDO_0005542 |
[Signs and symptoms related to acute ischemia of the myocardium secondary to coronary artery disease. The clinical presentation covers a spectrum of heart diseases from unstable angina to myocardial infarction.] |
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chronotype measurement
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EFO_0008328 |
[quantification of some aspect of chronotype such as ease of getting up in the morning] |
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heart rate variability
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CMO_0002812 |
[Heart rate variability (HRV) is the physiological phenomenon of variation in the time interval between heartbeats. It is measured by the variation in the beat-to-beat interval.] |
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epidermal growth factor receptor
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PR_000006933 |
[An EGF receptor type tyrosine-protein kinase that is a translation product of the human EGFR gene or a 1:1 ortholog thereof.] |
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cystatin-C
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PR_000005965 |
[A protein that is a translation product of the human CST3 gene or a 1:1 ortholog thereof.] |
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prostate cancer
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DOID_10283 |
[A male reproductive organ cancer that is located_in the prostate.] |
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lymphocyte
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CL_0000542 |
[A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.] |
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epigenetic biomarker
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BMONT_0000051 |
[A biomarker that measures epigenetic alterations, such as DNA methylation, histone methylation, histone acetylation, microRNAs, or other non-coding RNA.] |
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MicroRNA 124
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NCIT_C106407 |
[A 20 ribonucleotide sequence that is a final product of the processing of either MIR124-1 pre-miRNA, MIR124-2 pre-miRNA or MIR124-3 pre-miRNA. This oligonucleotide may be involved in the negative regulation of gene expression.] |